I am unfamiliar with some of the terminology used. Where can I find definitions?
All the scientific terms used by the MLPCN are defined in the NIH glossary.
What is a 'z' factor?
The robustness of an assay is evaluated by the coefficient called "Z-factor". It is reflective of both the assay signal dynamic range and the data variation associated with the signal measurements, and therefore, is suitable for assay quality assessment. The Z-factor is a dimensionless, simple statistical characteristic for each HTS assay. The Z-factor provides a useful tool for comparison and evaluation of the quality of assays, and can be utilized in assay optimization and validation. Publication: Journal of Biomolecular Screening, Vol. 4, No. 2, 67-73 (1999)
What diseases areas get funded?
There are no specific diseases designated for funding through this program. However, the SRSBSC focuses on pathogens that require BSL-2 or BSL-3 containment.How do I develop an assay?
An assay guidance manual is available on the NCGC website comprehensive guide for assay development.
What are the steps involved with this program?
Please see the screening process flow chart.
How can I apply for technical assistance from the MLPCN?
You can apply for technical assistance online at the NIH website.
How do I get further assistance with questions that I have about the program or grant application process?
The SRSBSC will provide additional assistance by telephone, email, or in-person consultation to Assay Providers committed to writing a grant application. Please contact Nichole Tower who can orchestrate team members to answer your needs.
